tryptoline has been researched along with 1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione in 1 studies
| Studies (tryptoline) | Trials (tryptoline) | Recent Studies (post-2010) (tryptoline) | Studies (1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione) | Trials (1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione) | Recent Studies (post-2010) (1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione) |
|---|---|---|---|---|---|
| 222 | 1 | 69 | 7 | 0 | 1 |
| Protein | Taxonomy | tryptoline (IC50) | 1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione (IC50) |
|---|---|---|---|
| Phospholipase C, gamma 1 | Homo sapiens (human) | 4.537 | |
| Apoptotic peptidase activating factor 1 | Homo sapiens (human) | 0.079 | |
| nuclear receptor corepressor 2 isoform 2 | Homo sapiens (human) | 4.691 | |
| caspase-9 isoform alpha precursor | Homo sapiens (human) | 0.145 | |
| dual specificity protein phosphatase 3 | Homo sapiens (human) | 10.2 | |
| caspase-3 isoform a preproprotein | Homo sapiens (human) | 0.145 | |
| cysteine protease ATG4B isoform a | Homo sapiens (human) | 2.07 | |
| peroxisome proliferator-activated receptor gamma isoform 2 | Homo sapiens (human) | 4.691 | |
| tyrosyl-DNA phosphodiesterase 2 | Homo sapiens (human) | 0.21 | |
| putative polyprotein | 0.5913 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
1 other study(ies) available for tryptoline and 1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |